What is Research?

Research is vital in providing the evidence we need to transform services and improve outcomes e.g. in developing new care models, redesigning urgent and emergency care, strengthening primary care and transforming mental health and cancer services.

By fully integrating research into our organisation we can outperform organisations that do not, leading to better quality care and improved use of resources.

"Pursuing the use of evidence and evaluation will improve how we measure the impact of our work, meaning we can learn from what works well, and what doesn’t. We wish to foster a culture in the NHS that seeks out research evidence and applies this evidence in decision-making. All of this will be underpinned by a strong infrastructure that is supportive of research and evaluation." NHS England.

Taking Part in Research

What is involved?

Your involvement and the time required depends on what is being investigated. The research team will be able to provide you with details.

Being involved in any trial is physically demanding and time consuming and while our clinical trials are open to patients that meet the criteria, the reality is that you may find it difficult to participate unless you are prepared to commit to frequent travel to Priory Gardens Surgery.

Please contact the Surgery before you consider taking part in a trial, information and questions you may wish to ask the research team.

What are the benefits in taking part?

There is evidence that for some conditions, patients involved with clinical trials have better long term outcomes and may also get earlier access to new drugs.

Your health will be closely monitored throughout any clinical trial. Any changes in your health, whether or not they are related to the treatment you are having, are frequently picked up and acted upon earlier than if you were not in a trial. However, some people find that the extra attention makes them worry more about their condition.

If you take part in a research study you:

    • will be helping others, and possibly yourself, by helping to identify more effective medical treatment
    • will have more contact with medical staff than you normally do
    • will have opportunities to learn more about your medical condition, which may help you to manage it better
    • may feel as though you are taking a more active role in your healthcare.

Many of our patients who have taken part in research have found it a positive and rewarding process.

How are patients selected?

All trials have defined patient requirements, specific to each trial. They may, for example, require patients to have a specific genetic makeup or specific stage of disease. Once these initial requirements have been assessed, candidates will be required to have a set of tests to check suitability for a trial.

Research makes a real difference to real people just like you!!!

Research Study and clinical trials at Priory Gardens Surgery

There are many different types of research studies and clinical trials which we are involved with, some look at improving current treatments; others focus on specific conditions or medical devices.

All of our studies and trials have to follow strict rules on medical ethics and have been approved by the relevant governing bodies. To find out more information on how studies within the NHS and England are approved and what is involved in clinical trials please refer to the NHS website’s clinical trials and medical research site.

Research studies and clinical trials rely on volunteers. Some involve healthy members of the public, while others involve patients taking part in a trial during their care and treatment.

If you are a patient at Priory Gardens Surgery, you may be invited to take part in a study or trial. It is entirely up to you whether or not you wish to get involved. If you decide not to participate, it will not affect your treatment in any way.

LIVE trials

At present we have research taking place in the following areas:

  • Children`s health- REST Study
  • Diabetes - GLoW Study
  • Aspirin therapy - ATTACK Study
  • Hypertension therapy - I_AM Study

Rest Study

To determine whether either ciprofloxacin drops, or delayed oral antibiotics are as good as current usual care (immediate oral antibiotics) for overall illness duration in children with acute otitis media (AOM) with discharge (AOMd) presenting to primary care.


Recruiting Criteria:

Child aged between ≥12 months and <16 years;

  • Presenting with recent onset (≤7 days) unilateral AOM with recent onset (≤7 days) otorrhoea currently visible (or seen by parent/legal guardian ≤24 hours);
  • Child attending with parent/legal guardian who is legally able to give consent in person;
  • Parent/legal guardian willing and able to administer ear drops;
  • Parent/legal guardian willing, able and available to complete the daily SRQ and received regular telephone calls from the study team.

Patient’s incentive:

  • £10 high street voucher for parents at the end of the study
  • £10 high street voucher for children aged between 10-16
  • Piggy bank for children under 10
  • Additional voucher will be sent to parents who take part longer interview.

Clinician:Dr Nasir Hannan

 GLoW Study

To evaluate the effect of a tailored diabetes education and behavioural weight management programme vs diabetes education on 12 month changes in glycated haemoglobin (HbA1c) in adults with a recent diagnosis of type 2 diabetes.

  • To evaluate the effect of a tailored diabetes education and behavioural weight management programme vs diabetes education on: − 6 and 12 month changes in weight, body fat percentage, blood pressure, lipid profile, and modelled cardiovascular risk − probability of achieving clinically significant weight loss, good glycaemic control or diabetes remission at 6 and 12 months − 6 and 12 month changes in diet and physical activity − 6 and 12 months changes in psychosocial factors associated with successful weight control.

 Recruiting Criteria:

  • Age≥18 years
  • BMI≥25kg/m2
  • Diagnosis of type 2 diabetes in previous 36 months
  • Capable of giving informed consent
  • Have a good understanding of the English language (study materials are not tailored to support non-English language speakers)
  • Willing to attend follow up visits at a local participating GP practice

Patient incentive:

  • Travel expenses reimbursed
  • High street voucher for attending £10 ( first visit and 6mths) £30 ( at 12mths)
  • Free advice on weight loss

Clinician: HCA Sarah Mead, Nurse Megan Eason and Nurse Jayne Collins

Attack Study

To test the hypothesis that the addition of 75mg aspirin once daily to usual care reduces the risk of major vascular events in patients with chronic kidney disease (CKD) who do not have pre-existing cardiovascular disease (CVD).


Recruiting Criteria:

  • Males and females aged 18+ at the date of screening.
  • Subjects with diagnosed CKD (estimated glomerular filtration rate [eGFR] <60mL/min/1.73m2 for at least 90 days and/or urine albumin: creatinine ratio [ACR] ≥3mg/mmol for at least 90 days).
  • Subjects, who are willing to give permission for their paper and electronic medical records to be accessed by trial investigators.
  • Subjects, who are willing to be contacted and interviewed by trial investigators.
  • Subjects, who can communicate well with the investigator or designee, understand the requirements.

Patient’s incentive:

  • Their prescriptions will be reimbursed on an annual basis (based on 4 x 3
  • monthly scripts per year).

 Clinician:  Dr Nasir Hannan, HCA Sarah Mead, HCA Rebecca Roberts


I_AM Study


Hypertension is a major risk factor for disability and premature death, and medication adherence can significantly lower these risks. However, large proportions of people do not take their medication as prescribed.

This service aims to provide you with tips on how to best take medication as prescribed; it provides advice based on evidence; it is interactive (e.g. you can ask and respond to questions, change the settings and content of the messages) and it can be easily personalised to your lifestyle (e.g. each person receives different reminders).

Recruiting Criteria:

  • Have a diagnosis of High Blood Pressure (HBP), or comorbidities of HBP: type 2 diabetes, cholesterol.
  • Are prescribed at least one antihypertensive medication (e.g. ACE inhibitors, beta blockers, calcium channel blockers, diuretics, alpha1 blockers, alpha2 agonists) for at least six months before study recruitment, as confirmed by practice records
  • Have poorly controlled HBP, as indicated by clinical measures (i.e. for treated HBP: blood pressure >140/90 mmHg if under 80 years old and >150/90 mmHg if over 80 years old. For people self-monitoring HBP at home or have white coat effect >135/85 mmHg if under 80 years and >145/85mmHg if over 80 years) during the last six months;
  • gaps in ordering or filling repeat prescriptions (i.e. Cumulative Medication Gap: CMG >0.20 for a duration of three months before recruitment).
  • Have a good understanding of English
  • Are able to use mobile phones
  • Have the capacity to provide informed consent.

Patient’s incentive:

  • support patients to self-monitor their medication taking
  • This intervention based on SMS/app will be available to provide advice on taking medication

Clinician: Nurse Megan Eason

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